This week looks like another tough one: How does USC respond in its first game without Lane Kiffin as head coach? Oregon gets its biggest test of the season and Georgia can't rest a week after losing multiple players to injury.

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Standings through six weeks:

Against the spread (last week):

42-18: Jon Cooper, SaturdayDownSouth.com (5-5)37-23: Mike Griffith, MLive.com (6-4)36-24: Bill Bender, Sporting News (6-4)35-25: Ken Bradley, Sporting News (3-7)34-26: David Matter, St. Louis Post-Dispatch (5-5)33-27: Teddy Greenstein, Chicago Tribune (4-6)30-30: Bill King, Host of On Campus with Bill King, 6-9 a.m., SiriusXM 91 (3-7)29-31: Andrew Carter, Raleigh News & Observer/Charlotte Observer (3-7)28-32: Matt Hayes, Sporting News (3-7)26-34: Mike Bianchi, Orlando Sentinel (3-7)

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Previous week’s picks: 1 | 2 | 3 | 4 | 5 | 6

Straight up:

47-13: Bill King, Host of On Campus with Bill King, 6-9 a.m., SiriusXM 91 (9-1)47-13: Matt Hayes, Sporting News (9-1)45-15: Bill Bender, Sporting News (10-0)45-15: Ken Bradley, Sporting News (8-2)45-15: Jon Cooper, SaturdayDownSouth.com (9-1)45-15: David Matter, St. Louis Post-Dispatch (9-1)44-16: Andrew Carter, Raleigh News & Observer/Charlotte Observer (9-1)44-16: Mike Griffith, MLive.com (10-0)42-18: Mike Bianchi, Orlando Sentinel (7-3)42-18: Teddy Greenstein, Chicago Tribune (9-1)

ARIZONA AT USC

Thursday, 10:30 p.m., Fox Sports 1

The line: USC (-5)

Bender: Arizona 38-35Bianchi: USC 24-21Bradley: Arizona 27-21Carter: USC 34-27Cooper: USC 31-28Greenstein: USC 24-17Griffith: USC 27-20Hayes: Arizona 33-21King: Arizona 31-24Matter: USC 24-21

MISSOURI AT GEORGIA

Saturday, noon, ESPN

The line: Georgia (-10.5)

Bender: Georgia 38-27Bianchi: Missouri 34-30Bradley: Georgia 45-28Carter: Georgia 40-21Cooper: Georgia 41-38Greenstein: Missouri 40-34Griffith: Georgia 31-20Hayes: Georgia 31-30King: Georgia 28-24Matter: Georgia 37-34

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OKLAHOMA VS. TEXAS, DALLAS

Saturday, noon, ABC

The line: Oklahoma (-12.5)

Bender: Oklahoma 34-20Bianchi: Oklahoma 42-28Bradley: Oklahoma 40-24Carter: Oklahoma 33-24Cooper: Oklahoma 45-14Greenstein: Oklahoma 29-23Griffith: Oklahoma 33-20Hayes: Oklahoma 30-21King: Oklahoma 31-21Matter: Oklahoma 31-14

PITTSBURGH AT VIRGINIA TECH

Saturday, noon, ESPNU

The line: Virginia Tech (-9)

Bender: Virginia Tech 34-20Bianchi: Virginia Tech 27-21Bradley: Virginia Tech 30-14Carter: Pittsburgh 24-21Cooper: Virginia Tech 24-14Greenstein: Virginia Tech 27-16Griffith: Virginia Tech 24-17Hayes: Virginia Tech 19-16King: Virginia Tech 24-21Matter: Virginia Tech 27-20

FLORIDA AT LSU

Saturday, 3:30 p.m., CBS

The line: LSU (-7)

Bender: LSU 34-24Bianchi: LSU 27-17Bradley: LSU 30-17Carter: Florida 21-20Cooper: LSU 31-26Greenstein: LSU 30-14Griffith: LSU 20-10Hayes: Florida 24-21King: LSU 28-27Matter: LSU 28-20

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SOUTH CAROLINA AT ARKANSAS

Saturday, 12:21, ESPN3

The line: South Carolina (-7)

Bender: Arkansas 24-23Bianchi: Arkansas 22-21Bradley: South Carolina 30-24Carter: South Carolina 27-17Cooper: South Carolina 31-21Greenstein: South Carolina 27-17Griffith: South Carolina 24-20Hayes: South Carolina 27-23King: South Carolina 35-28Matter: South Carolina 27-21

FIRST-AND-10: Clowney dropping red flags

NORTHWESTERN AT WISCONSIN

Saturday, 3:30 p.m., ABC/ESPN2

The line: Wisconsin (-10)

Bender: Northwestern 47-44Bianchi: Wisconsin 30-20Bradley: Northwestern 34-31Carter: Wisconsin 30-17Cooper: Wisconsin 27-24Greenstein: Wisconsin 31-24Griffith: Wisconsin 27-20Hayes: Wisconsin 30-28King: Wisconsin 38-34Matter: Wisconsin 34-21

OREGON AT WASHINGTON

Saturday, 4 p.m., Fox Sports 1

The line: Oregon (-14.5)

Bender: Oregon 44-28Bianchi: Oregon 42-34Bradley: Oregon 47-34Carter: Oregon 37-24Cooper: Oregon 48-31Greenstein: Oregon 34-24Griffith: Oregon 37-20Hayes: Oregon 41-30King: Oregon 38-28Matter: Oregon 44-27

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TEXAS A&M AT OLE MISS

Saturday, 8:30 p.m., ESPN

The line: Texas A&M (-7)

Bender: Texas A&M 51-45Bianchi: Texas A&M 35-30Bradley: Texas A&M 45-31Carter: Texas A&M 33-20Cooper: Texas A&M 49-41Greenstein: Texas A&M 41-21Griffith: Texas A&M 31-28Hayes: Texas A&M 31-24King: Texas A&M 45-31Matter: Texas A&M 41-28

MICHIGAN AT PENN STATE

Saturday, 5 p.m., ESPN

The line: Michigan (-3)

Bender: Michigan 27-23Bianchi: Michigan 22-20Bradley: Michigan 30-24Carter: Penn State 28-27Cooper: Michigan 27-23Greenstein: Penn State 21-17Griffith: Michigan 20-18Hayes: Michigan 24-16King: Michigan 24-17Matter: Michigan 31-21