No. 3 Clemson will face Lamar Jackson and No. 14 Louisville at 8 p.m. on ABC. Both teams have opened the season with two straight wins.
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Meanwhile, No. 23 Tennessee is set to take on No. 24 Florida at 3:30 p.m. on CBS in an SEC East contest, while Texas travels to No. 4 USC in a rematch of the 2006 BCS national championship game.
Here’s how you can watch every AP Top 25 team in action this week (all times Eastern).
Note: No. 17 Miami at No. 11 Florida State, originally scheduled for Sept. 16, has been postponed until Oct. 7 due to the effects of Hurricane Irma.